Complete regression of human malignant mesothelioma xenografts following local injection of midkine promoter-driven oncolytic adenovirus

BACKGROUND: Malignant mesothelioma is a highly aggressive tumor with poor prognosis. Conventional therapies for mesothelioma are generally non-curative, and new treatment paradigms are urgently needed. We hypothesized that the tumor-specific midkine (Mdk) promoter could confer transcriptional target...

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Bibliografiset tiedot
Päätekijät: Kubo, Shuji, Kawasaki, Yoshiko, Yamaoka, Norie, Tagawa, Masatoshi, Kasahara, Noriyuki, Terada, Nobuyuki, Okamura, Haruki
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938764/
https://ncbi.nlm.nih.gov/pubmed/20635326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.1486
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