Llwytho...

Mitochondrial dysfunction and apoptosis underlie the hepatotoxicity of perhexiline

Perhexiline is an anti-anginal drug developed in the late 1960s. Despite its therapeutic success, it caused severe hepatoxicity in selective patients, which resulted in its withdrawal from the market. In the current study we explored the molecular mechanisms underlying the cytotoxicity of perhexilin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Toxicol In Vitro
Prif Awduron: Ren, Zhen, Chen, Si, Seo, Ji-Eun, Guo, Xiaoqing, Li, Dongying, Ning, Baitang, Guo, Lei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7938330/
https://ncbi.nlm.nih.gov/pubmed/32861758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2020.104987
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