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Mitochondrial dysfunction and apoptosis underlie the hepatotoxicity of perhexiline
Perhexiline is an anti-anginal drug developed in the late 1960s. Despite its therapeutic success, it caused severe hepatoxicity in selective patients, which resulted in its withdrawal from the market. In the current study we explored the molecular mechanisms underlying the cytotoxicity of perhexilin...
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| Udgivet i: | Toxicol In Vitro |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7938330/ https://ncbi.nlm.nih.gov/pubmed/32861758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2020.104987 |
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