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Deubiquitinase OTUD5 is a positive regulator of mTORC1 and mTORC2 signaling pathways

The mammalian Target of Rapamycin (mTOR) pathway regulates a variety of physiological processes, including cell growth and cancer progression. The regulatory mechanisms of these signals are extremely complex and comprise many feedback loops. Here, we identified the deubiquitinating enzyme ovarian tu...

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Veröffentlicht in:Cell Death Differ
Hauptverfasser: Cho, Jin Hwa, Kim, Kidae, Kim, Sung Ah, Park, Sungryul, Park, Bi-Oh, Kim, Jong-Hwan, Kim, Seon-Young, Kwon, Min Jee, Han, Myeong Hoon, Lee, Sung Bae, Park, Byoung Chul, Park, Sung Goo, Kim, Jeong-Hoon, Kim, Sunhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937674/
https://ncbi.nlm.nih.gov/pubmed/33110214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00649-z
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