Effect of Food on the Pharmacokinetics of the Oral Docetaxel Tablet Formulation ModraDoc006 Combined with Ritonavir (ModraDoc006/r) in Patients with Advanced Solid Tumours

INTRODUCTION: ModraDoc006 is a novel docetaxel tablet formulation that is co-administrated with the cytochrome P450 3A4 and P-glycoprotein inhibitor ritonavir (r): ModraDoc006/r. OBJECTIVES: This study evaluated the effect of food consumed prior to administration of ModraDoc006/r on the pharmacokine...

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Vydáno v:Drugs R D
Hlavní autoři: Vermunt, Marit A. C., de Weger, Vincent A., Janssen, Julie M., Lopez-Yurda, Marta I., Keessen, Marianne, Thijssen, Bas, Rosing, Hilde, Huitema, Alwin D. R., Beijnen, Jos H., Marchetti, Serena
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2021
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Original Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7937587/
https://ncbi.nlm.nih.gov/pubmed/33464545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-020-00336-x
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