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Development of a Tumour Growth Inhibition Model to Elucidate the Effects of Ritonavir on Intratumoural Metabolism and Anti-tumour Effect of Docetaxel in a Mouse Model for Hereditary Breast Cancer

In a mouse tumour model for hereditary breast cancer, we previously explored the anti-cancer effects of docetaxel, ritonavir and the combination of both and studied the effect of ritonavir on the intratumoural concentration of docetaxel. The objective of the current study was to apply pharmacokineti...

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Detalhes bibliográficos
Publicado no:AAPS J
Main Authors: Yu, Huixin, Hendrikx, Jeroen J. M. A., Rottenberg, Sven, Schellens, Jan H. M., Beijnen, Jos H., Huitema, Alwin D. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779112/
https://ncbi.nlm.nih.gov/pubmed/26603889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-015-9838-1
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