VE-1902—A direct thrombin inhibitor with reversible covalent mechanism of action shows efficacy with reduced bleeding in rodent models of thrombosis

INTRODUCTION: High incidence of bleeding events remains a key risk for patients taking anticoagulants, especially those in need of long-term combination therapy with antiplatelet agents. As a consequence, patients may not receive clinically indicated combination antithrombotic therapy. Here, we repo...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Thromb Res
Main Authors: Sivaraja, Mohanram, Clemens, Daniel M., Sizikov, Sivan, Dash, Subhadra, Xu, Chengpei, Rienzo, Matthew, Yang, Bo, Ryan, Molly, Chattopadhyay, Madhuri, Igoudin, Lev, Chang, Stephanie S., Keutzer, Samuel, Zalicki, Piotr, Estiarte, M. Angels, Shiau, Timothy P., Short, Kevin M., Williams, David C., Datta, Anirban, Pozzi, Nicola, Di Cera, Enrico, Gibson, C. Michael, Fox, Keith A.A., Kita, David B.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2020
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7936662/
https://ncbi.nlm.nih.gov/pubmed/32339947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2020.04.020
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