Design of immunogens to elicit broadly neutralizing antibodies against HIV targeting the CD4 binding site

A vaccine which is effective against the HIV virus is considered to be the best solution to the ongoing global HIV/AIDS epidemic. In the past thirty years, numerous attempts to develop an effective vaccine have been made with little or no success, due, in large part, to the high mutability of the vi...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Conti, Simone, Kaczorowski, Kevin J., Song, Ge, Porter, Katelyn, Andrabi, Raiees, Burton, Dennis R., Chakraborty, Arup K., Karplus, Martin
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2021
Fag:
Physical Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7936365/
https://ncbi.nlm.nih.gov/pubmed/33637649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2018338118
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