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Design of immunogens to elicit broadly neutralizing antibodies against HIV targeting the CD4 binding site

A vaccine which is effective against the HIV virus is considered to be the best solution to the ongoing global HIV/AIDS epidemic. In the past thirty years, numerous attempts to develop an effective vaccine have been made with little or no success, due, in large part, to the high mutability of the vi...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Conti, Simone, Kaczorowski, Kevin J., Song, Ge, Porter, Katelyn, Andrabi, Raiees, Burton, Dennis R., Chakraborty, Arup K., Karplus, Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7936365/
https://ncbi.nlm.nih.gov/pubmed/33637649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2018338118
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