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Computational Prediction of Broadly Neutralizing HIV-1 Antibody Epitopes from Neutralization Activity Data

Broadly neutralizing monoclonal antibodies effective against the majority of circulating isolates of HIV-1 have been isolated from a small number of infected individuals. Definition of the conformational epitopes on the HIV spike to which these antibodies bind is of great value in defining targets f...

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Detalhes bibliográficos
Main Authors: Ferguson, Andrew L., Falkowska, Emilia, Walker, Laura M., Seaman, Michael S., Burton, Dennis R., Chakraborty, Arup K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846483/
https://ncbi.nlm.nih.gov/pubmed/24312481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080562
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