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Role of framework mutations and antibody flexibility in the evolution of broadly neutralizing antibodies
Eliciting antibodies that are cross reactive with surface proteins of diverse strains of highly mutable pathogens (e.g., HIV, influenza) could be key for developing effective universal vaccines. Mutations in the framework regions of such broadly neutralizing antibodies (bnAbs) have been reported to...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5828663/ https://ncbi.nlm.nih.gov/pubmed/29442996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33038 |
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