A carregar...

Targeting the mutant PIK3CA gene by DNA‐alkylating pyrrole‐imidazole polyamide in cervical cancer

PIK3CA is the most frequently mutated oncogene in cervical cancer, and somatic mutations in the PIK3CA gene result in increased activity of PI3K. In cervical cancer, the E545K mutation in PIK3CA leads to elevated cell proliferation and reduced apoptosis. In the present study, we designed and synthes...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Krishnamurthy, Sakthisri, Yoda, Hiroyuki, Hiraoka, Kiriko, Inoue, Takahiro, Lin, Jason, Shinozaki, Yoshinao, Watanabe, Takayoshi, Koshikawa, Nobuko, Takatori, Atsushi, Nagase, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7935806/
https://ncbi.nlm.nih.gov/pubmed/33377228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14785
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!