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The Road Not Taken with Pyrrole-Imidazole Polyamides: Off-Target Effects and Genomic Binding

The high sequence specificity of minor groove-binding N-methylpyrrole-N-methylimidazole polyamides have made significant advances in cancer and disease biology, yet there have been few comprehensive reports on their off-target effects, most likely as a consequence of the lack of available tools in e...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Lin, Jason, Nagase, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226143/
https://ncbi.nlm.nih.gov/pubmed/32260120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10040544
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