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Repurposing calcium-sensing receptor agonist cinacalcet for treatment of CFTR-mediated secretory diarrheas

Diarrhea is a major cause of global mortality, and outbreaks of secretory diarrhea such as cholera remain an important problem in the developing world. Current treatment of secretory diarrhea primarily involves supportive measures, such as fluid replacement. The calcium-sensing receptor (CaSR) regul...

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Foilsithe in:JCI Insight
Main Authors: Oak, Apurva A., Chhetri, Parth D., Rivera, Amber A., Verkman, Alan S., Cil, Onur
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934922/
https://ncbi.nlm.nih.gov/pubmed/33400691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.146823
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