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Repurposing calcium-sensing receptor agonist cinacalcet for treatment of CFTR-mediated secretory diarrheas

Diarrhea is a major cause of global mortality, and outbreaks of secretory diarrhea such as cholera remain an important problem in the developing world. Current treatment of secretory diarrhea primarily involves supportive measures, such as fluid replacement. The calcium-sensing receptor (CaSR) regul...

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Publicado en:JCI Insight
Main Authors: Oak, Apurva A., Chhetri, Parth D., Rivera, Amber A., Verkman, Alan S., Cil, Onur
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934922/
https://ncbi.nlm.nih.gov/pubmed/33400691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.146823
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