Exhausted-like CD8(+) T cell phenotypes linked to C-peptide preservation in alefacept-treated T1D subjects

Clinical trials of biologic therapies in type 1 diabetes (T1D) aim to mitigate autoimmune destruction of pancreatic β cells through immune perturbation and serve as resources to elucidate immunological mechanisms in health and disease. In the T1DAL trial of alefacept (LFA3-Ig) in recent-onset T1D, e...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:JCI Insight
Päätekijät: Diggins, Kirsten E., Serti, Elisavet, Muir, Virginia, Rosasco, Mario, Lu, TingTing, Balmas, Elisa, Nepom, Gerald, Long, S. Alice, Linsley, Peter S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2021
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934874/
https://ncbi.nlm.nih.gov/pubmed/33351781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.142680
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia