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Partial exhaustion of CD8 T cells and clinical response to teplizumab in new-onset type 1 diabetes
Biologic treatment of T1D typically results in transient stabilization of C-peptide levels (a surrogate for endogenous insulin secretion) in some patients, followed by progression at the same rate as in untreated control groups. Here, we used integrated systems biology and flow cytometry approaches...
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| Publicado no: | Sci Immunol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5486405/ https://ncbi.nlm.nih.gov/pubmed/28664195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aai7793 |
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