HIV-specific T cell responses reflect substantive in vivo interactions with antigen despite long-term therapy

Antiretroviral therapies (ARTs) abrogate HIV replication; however, infection persists as long-lived reservoirs of infected cells with integrated proviruses, which reseed replication if ART is interrupted. A central tenet of our current understanding of this persistence is that infected cells are shi...

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Vydáno v:JCI Insight
Hlavní autoři: Stevenson, Eva M., Ward, Adam R., Truong, Ronald, Thomas, Allison S., Huang, Szu-Han, Dilling, Thomas R., Terry, Sandra, Bui, John K., Mota, Talia M., Danesh, Ali, Lee, Guinevere Q., Gramatica, Andrea, Khadka, Pragya, Alberto, Winiffer D. Conce, Gandhi, Rajesh T., McMahon, Deborah K., Lalama, Christina M., Bosch, Ronald J., Macatangay, Bernard, Cyktor, Joshua C., Eron, Joseph J., Mellors, John W., Jones, R. Brad
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934865/
https://ncbi.nlm.nih.gov/pubmed/33400687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.142640
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