HIV-specific T cell responses reflect substantive in vivo interactions with antigen despite long-term therapy

Antiretroviral therapies (ARTs) abrogate HIV replication; however, infection persists as long-lived reservoirs of infected cells with integrated proviruses, which reseed replication if ART is interrupted. A central tenet of our current understanding of this persistence is that infected cells are shi...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Stevenson, Eva M., Ward, Adam R., Truong, Ronald, Thomas, Allison S., Huang, Szu-Han, Dilling, Thomas R., Terry, Sandra, Bui, John K., Mota, Talia M., Danesh, Ali, Lee, Guinevere Q., Gramatica, Andrea, Khadka, Pragya, Alberto, Winiffer D. Conce, Gandhi, Rajesh T., McMahon, Deborah K., Lalama, Christina M., Bosch, Ronald J., Macatangay, Bernard, Cyktor, Joshua C., Eron, Joseph J., Mellors, John W., Jones, R. Brad
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934865/
https://ncbi.nlm.nih.gov/pubmed/33400687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.142640
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