Dysregulated SREBP1c/miR-153 signaling induced by hypertriglyceridemia worsens acute pancreatitis and delays tissue repair

Severe acute pancreatitis (AP) is a life-threatening disease with up to 30% mortality. Therefore, prevention of AP aggravation and promotion of pancreatic regeneration are critical during the course and treatment of AP. Hypertriglyceridemia (HTG) is an established aggravating factor for AP that hind...

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Pubblicato in:JCI Insight
Autori principali: Dai, Juanjuan, Jiang, Mingjie, Hu, Yangyang, Xiao, Jingbo, Hu, Bin, Xu, Jiyao, Han, Xiao, Shen, Shuangjun, Li, Bin, Wu, Zengkai, He, Yan, Ren, Yingchun, Wen, Li, Wang, Xingpeng, Hu, Guoyong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934861/
https://ncbi.nlm.nih.gov/pubmed/33491670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.138584
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