SRSF1 inhibits autophagy through regulating Bcl-x splicing and interacting with PIK3C3 in lung cancer

Alternative splicing is a critical process to generate protein diversity. However, whether and how alternative splicing regulates autophagy remains largely elusive. Here we systematically identify the splicing factor SRSF1 as an autophagy suppressor. Specifically, SRSF1 inhibits autophagosome format...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Signal Transduct Target Ther
Main Authors: Lv, Yuesheng, Zhang, Wenjing, Zhao, Jinyao, Sun, Bing, Qi, Yangfan, Ji, Haoyu, Chen, Chaoqun, Zhang, Jinrui, Sheng, Junxiu, Wang, Taishu, Dominguez, Daniel, Liu, Han, Liu, Quentin, Meng, Songshu, Li, Xiaoling, Wang, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933324/
https://ncbi.nlm.nih.gov/pubmed/33664238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-021-00495-6
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados