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N-Glycosylation can selectively block or foster different receptor–ligand binding modes
While DNA encodes protein structure, glycans provide a complementary layer of information to protein function. As a prime example of the significance of glycans, the ability of the cell surface receptor CD44 to bind its ligand, hyaluronan, is modulated by N-glycosylation. However, the details of thi...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7933184/ https://ncbi.nlm.nih.gov/pubmed/33664400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84569-z |
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