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Optimization of the crystallizability of a single-chain antibody fragment
Single-chain variable antibody fragments (scFvs) are molecules with immense therapeutic and diagnostic potential. Knowledge of their three-dimensional structure is important for understanding their antigen-binding mode as well as for protein-engineering approaches such as antibody humanization. A ma...
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| Publicado no: | Acta Crystallogr F Struct Biol Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4259244/ https://ncbi.nlm.nih.gov/pubmed/25484230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X1402247X |
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