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Excessive aggregation of membrane proteins in the Martini model

The coarse-grained Martini model is employed extensively to study membrane protein oligomerization. While this approach is exceptionally promising given its computational efficiency, it is alarming that a significant fraction of these studies demonstrate unrealistic protein clusters, whose formation...

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Vydáno v:PLoS One
Hlavní autoři: Javanainen, Matti, Martinez-Seara, Hector, Vattulainen, Ilpo
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5683612/
https://ncbi.nlm.nih.gov/pubmed/29131844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187936
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