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Protein synthesis with conformationally constrained cyclic dipeptides

We have synthesized several conformationally constrained dipeptide analogues as possible substrates for incorporation into proteins. These have included three cyclic dipeptides formed from Boc derivatives of 2,4-diaminobutyric acid, ornithine and lysine, having 5-, 6-, and 7-membered lactam rings, r...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Zhang, Chao, Bai, Xiaoguang, Dedkova, Larisa M., Hecht, Sidney M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933035/
https://ncbi.nlm.nih.gov/pubmed/33007560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2020.115780
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