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Synthesis of fluorescent dipeptidomimetics and their ribosomal incorporation into green fluorescent protein

The synthesis and incorporation into position 66 of green fluorescent protein (GFP) by in vitro protein translation of novel oxazole and thiazole based dipeptidomimetics are described. The compounds may be regarded as GFP chromophore analogues, and are strongly fluorescent. An α-amido-β-ketoester in...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Chowdhury, Sandipan Roy, Maini, Rumit, Dedkova, Larisa M., Hecht, Sidney M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607672/
https://ncbi.nlm.nih.gov/pubmed/26351043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.08.073
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