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Ribosome-Mediated Incorporation of Dipeptides and Dipeptide Analogues into Proteins in Vitro

Plasmids containing 23S rRNA randomized at positions 2057−2063 and 2502−2507 were introduced into Escherichia coli, affording a library of clones which produced modified ribosomes in addition to the preexisting wild-type ribosomes. These clones were screened with a derivative of puromycin, a natural...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Maini, Rumit, Dedkova, Larisa M., Paul, Rakesh, Madathil, Manikandadas M., Chowdhury, Sandipan Roy, Chen, Shengxi, Hecht, Sidney M.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5724524/
https://ncbi.nlm.nih.gov/pubmed/26301427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b03135
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