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Ribosome-Mediated Incorporation of Dipeptides and Dipeptide Analogues into Proteins in Vitro
Plasmids containing 23S rRNA randomized at positions 2057−2063 and 2502−2507 were introduced into Escherichia coli, affording a library of clones which produced modified ribosomes in addition to the preexisting wild-type ribosomes. These clones were screened with a derivative of puromycin, a natural...
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| Veröffentlicht in: | J Am Chem Soc |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5724524/ https://ncbi.nlm.nih.gov/pubmed/26301427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b03135 |
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