A novel hypoxic long noncoding RNA KB-1980E6.3 maintains breast cancer stem cell stemness via interacting with IGF2BP1 to facilitate c-Myc mRNA stability

The hostile hypoxic microenvironment takes primary responsibility for the rapid expansion of breast cancer tumors. However, the underlying mechanism is not fully understood. Here, using RNA sequencing (RNA-seq) analysis, we identified a hypoxia-induced long noncoding RNA (lncRNA) KB-1980E6.3, which...

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Publicado no:Oncogene
Main Authors: Zhu, Pengpeng, He, Fang, Hou, Yixuan, Tu, Gang, Li, Qiao, Jin, Ting, Zeng, Huan, Qin, Yilu, Wan, Xueying, Qiao, Yina, Qiu, Yuxiang, Teng, Yong, Liu, Manran
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7932928/
https://ncbi.nlm.nih.gov/pubmed/33469161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01638-9
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