A novel hypoxic long noncoding RNA KB-1980E6.3 maintains breast cancer stem cell stemness via interacting with IGF2BP1 to facilitate c-Myc mRNA stability

The hostile hypoxic microenvironment takes primary responsibility for the rapid expansion of breast cancer tumors. However, the underlying mechanism is not fully understood. Here, using RNA sequencing (RNA-seq) analysis, we identified a hypoxia-induced long noncoding RNA (lncRNA) KB-1980E6.3, which...

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Vydáno v:Oncogene
Hlavní autoři: Zhu, Pengpeng, He, Fang, Hou, Yixuan, Tu, Gang, Li, Qiao, Jin, Ting, Zeng, Huan, Qin, Yilu, Wan, Xueying, Qiao, Yina, Qiu, Yuxiang, Teng, Yong, Liu, Manran
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7932928/
https://ncbi.nlm.nih.gov/pubmed/33469161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01638-9
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