FOSL2 promotes VEGF-independent angiogenesis by transcriptionnally activating Wnt5a in breast cancer-associated fibroblasts

Cancer-associated fibroblasts (CAFs), a predominant component of the tumor microenvironment, contribute to aggressive angiogenesis progression. In clinical practice, traditional anti-angiogenic therapy, mainly anti-VEGF, provides extremely limited beneficial effects to breast cancer. Here, we reveal...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Wan, Xueying, Guan, Shengdong, Hou, Yixuan, Qin, Yilu, Zeng, Huan, Yang, Liping, Qiao, Yina, Liu, Shuiqing, Li, Qiao, Jin, Ting, Qiu, Yuxiang, Liu, Manran
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2021
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7978317/
https://ncbi.nlm.nih.gov/pubmed/33754039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.55074
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