TGx-DDI, a Transcriptomic Biomarker for Genotoxicity Hazard Assessment of Pharmaceuticals and Environmental Chemicals

Genotoxicity testing is an essential component of the safety assessment paradigm required by regulatory agencies world-wide for analysis of drug candidates, and environmental and industrial chemicals. Current genotoxicity testing batteries feature a high incidence of irrelevant positive findings—par...

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Vydáno v:Front Big Data
Hlavní autoři: Li, Heng-Hong, Yauk, Carole L., Chen, Renxiang, Hyduke, Daniel R., Williams, Andrew, Frötschl, Roland, Ellinger-Ziegelbauer, Heidrun, Pettit, Syril, Aubrecht, Jiri, Fornace, Albert J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Big Data
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7931968/
https://ncbi.nlm.nih.gov/pubmed/33693359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fdata.2019.00036
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