Assessment of the performance of the TGx‐DDI biomarker to detect DNA damage‐inducing agents using quantitative RT‐PCR in TK6 cells

Gene expression biomarkers are now available for application in the identification of genotoxic hazards. The TGx‐DDI transcriptomic biomarker can accurately distinguish DNA damage‐inducing (DDI) from non‐DDI exposures based on changes in the expression of 64 biomarker genes. The 64 genes were previo...

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Bibliografski detalji
Izdano u:Environ Mol Mutagen
Glavni autori: Cho, Eunnara, Buick, Julie K., Williams, Andrew, Chen, Renxiang, Li, Heng‐Hong, Corton, J. Christopher, Fornace, Albert J., Aubrecht, Jiri, Yauk, Carole L.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2018
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588084/
https://ncbi.nlm.nih.gov/pubmed/30488505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22257
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