Assessment of the performance of the TGx‐DDI biomarker to detect DNA damage‐inducing agents using quantitative RT‐PCR in TK6 cells

Gene expression biomarkers are now available for application in the identification of genotoxic hazards. The TGx‐DDI transcriptomic biomarker can accurately distinguish DNA damage‐inducing (DDI) from non‐DDI exposures based on changes in the expression of 64 biomarker genes. The 64 genes were previo...

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Detalhes bibliográficos
Publicado no:Environ Mol Mutagen
Main Authors: Cho, Eunnara, Buick, Julie K., Williams, Andrew, Chen, Renxiang, Li, Heng‐Hong, Corton, J. Christopher, Fornace, Albert J., Aubrecht, Jiri, Yauk, Carole L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588084/
https://ncbi.nlm.nih.gov/pubmed/30488505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22257
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