Assessment of the performance of the TGx‐DDI biomarker to detect DNA damage‐inducing agents using quantitative RT‐PCR in TK6 cells

Gene expression biomarkers are now available for application in the identification of genotoxic hazards. The TGx‐DDI transcriptomic biomarker can accurately distinguish DNA damage‐inducing (DDI) from non‐DDI exposures based on changes in the expression of 64 biomarker genes. The 64 genes were previo...

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Dettagli Bibliografici
Pubblicato in:Environ Mol Mutagen
Autori principali: Cho, Eunnara, Buick, Julie K., Williams, Andrew, Chen, Renxiang, Li, Heng‐Hong, Corton, J. Christopher, Fornace, Albert J., Aubrecht, Jiri, Yauk, Carole L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2018
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588084/
https://ncbi.nlm.nih.gov/pubmed/30488505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22257
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