Integration of metabolic activation with a predictive toxicogenomics signature to classify genotoxic versus nongenotoxic chemicals in human TK6 cells

The use of integrated approaches in genetic toxicology, including the incorporation of gene expression data to determine the molecular pathways involved in the response, is becoming more common. In a companion article, a genomic biomarker was developed in human TK6 cells to classify chemicals as gen...

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Publicado en:Environ Mol Mutagen
Autores principales: Buick, Julie K., Moffat, Ivy, Williams, Andrew, Swartz, Carol D., Recio, Leslie, Hyduke, Daniel R., Li, Heng‐Hong, Fornace, Albert J., Aubrecht, Jiri, Yauk, Carole L.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2015
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506226/
https://ncbi.nlm.nih.gov/pubmed/25733247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.21940
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