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Development of a toxicogenomics signature for genotoxicity using a dose-optimization and informatics strategy in human cells
The development of in vitro molecular biomarkers to accurately predict toxicological effects has become a priority to advance testing strategies for human health risk assessment. The application of in vitro transcriptomic biomarkers promises increased throughput as well as a reduction in animal use....
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| Publicado en: | Environ Mol Mutagen |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506269/ https://ncbi.nlm.nih.gov/pubmed/25733355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.21941 |
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