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Phase separation of Axin organizes the β-catenin destruction complex

In Wnt/β-catenin signaling, the β-catenin protein level is deliberately controlled by the assembly of the multiprotein β-catenin destruction complex composed of Axin, adenomatous polyposis coli (APC), glycogen synthase kinase 3β (GSK3β), casein kinase 1α (CK1α), and others. Here we provide compellin...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Nong, Junxiu, Kang, Kexin, Shi, Qiaoni, Zhu, Xuechen, Tao, Qinghua, Chen, Ye-Guang
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7931644/
https://ncbi.nlm.nih.gov/pubmed/33651074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202012112
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