Caricamento...
Destruction complex dynamics: Wnt/β-catenin signaling alters Axin-GSK3β interactions in vivo
The central regulator of the Wnt/β-catenin pathway is the Axin/APC/GSK3β destruction complex (DC), which, under unstimulated conditions, targets cytoplasmic β-catenin for degradation. How Wnt activation inhibits the DC to permit β-catenin-dependent signaling remains controversial, in part because th...
Salvato in:
| Pubblicato in: | Development |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Company of Biologists Ltd
2019
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6633605/ https://ncbi.nlm.nih.gov/pubmed/31189665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.164145 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|