Exploring the Potential of Cytochrome P450 CYP109B1 Catalyzed Regio—and Stereoselective Steroid Hydroxylation

Cytochrome P450 enzyme CYP109B1 is a versatile biocatalyst exhibiting hydroxylation activities toward various substrates. However, the regio- and stereoselective steroid hydroxylation by CYP109B1 is far less explored. In this study, the oxidizing activity of CYP109B1 is reconstituted by coupling red...

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Библиографические подробности
Опубликовано в: :Front Chem
Главные авторы: Zhang, Xiaodong, Hu, Yun, Peng, Wei, Gao, Chenghua, Xing, Qiong, Wang, Binju, Li, Aitao
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Chemistry
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930613/
https://ncbi.nlm.nih.gov/pubmed/33681151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2021.649000
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