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Expression of the MexXY Aminoglycoside Efflux Pump and Presence of an Aminoglycoside-Modifying Enzyme in Clinical Pseudomonas aeruginosa Isolates Are Highly Correlated

The impact of MexXY efflux pump expression on aminoglycoside resistance in clinical Pseudomonas aeruginosa isolates has been debated. In this study, we found that, in general, elevated mexXY gene expression levels in clinical P. aeruginosa isolates confer to slight increases in aminoglycoside MIC le...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Seupt, Alexander, Schniederjans, Monika, Tomasch, Jürgen, Häussler, Susanne
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927871/
https://ncbi.nlm.nih.gov/pubmed/33046496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01166-20
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