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Expression of the MexXY Aminoglycoside Efflux Pump and Presence of an Aminoglycoside-Modifying Enzyme in Clinical Pseudomonas aeruginosa Isolates Are Highly Correlated

The impact of MexXY efflux pump expression on aminoglycoside resistance in clinical Pseudomonas aeruginosa isolates has been debated. In this study, we found that, in general, elevated mexXY gene expression levels in clinical P. aeruginosa isolates confer to slight increases in aminoglycoside MIC le...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Seupt, Alexander, Schniederjans, Monika, Tomasch, Jürgen, Häussler, Susanne
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927871/
https://ncbi.nlm.nih.gov/pubmed/33046496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01166-20
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