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New Amides Containing Selenium as Potent Leishmanicidal Agents Targeting Trypanothione Reductase
Two new series of 28 selenocyanate and diselenide derivatives containing amide moieties were designed, synthesized, and evaluated for their leishmanicidal activity against Leishmania infantum axenic amastigotes, and selectivity was assessed in human THP-1 cells. Eleven compounds exhibited excellent...
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| Vydáno v: | Antimicrob Agents Chemother |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7927869/ https://ncbi.nlm.nih.gov/pubmed/33046492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00524-20 |
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