New Amides Containing Selenium as Potent Leishmanicidal Agents Targeting Trypanothione Reductase

Two new series of 28 selenocyanate and diselenide derivatives containing amide moieties were designed, synthesized, and evaluated for their leishmanicidal activity against Leishmania infantum axenic amastigotes, and selectivity was assessed in human THP-1 cells. Eleven compounds exhibited excellent...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Etxebeste-Mitxeltorena, Mikel, Plano, Daniel, Espuelas, Socorro, Moreno, Esther, Aydillo, Carlos, Jiménez-Ruiz, Antonio, Soriano, Juan Carlos García, Sanmartín, Carmen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Chemistry; Biosynthesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927869/
https://ncbi.nlm.nih.gov/pubmed/33046492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00524-20
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker