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KRAB-ZFP Transcriptional Regulators Acting as Oncogenes and Tumor Suppressors: An Overview

Krüppel-associated box zinc finger proteins (KRAB-ZFPs) constitute the largest family of transcriptional factors exerting co-repressor functions in mammalian cells. In general, KRAB-ZFPs have a dual structure. They may bind to specific DNA sequences via zinc finger motifs and recruit a repressive co...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Sobocińska, Joanna, Molenda, Sara, Machnik, Marta, Oleksiewicz, Urszula
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7926519/
https://ncbi.nlm.nih.gov/pubmed/33672287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22042212
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