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ZFP226 is a novel artificial transcription factor for selective activation of tumor suppressor KIBRA

KIBRA has been suggested as a key regulator of the hippo pathway, regulating organ size, cell contact inhibition as well as tissue regeneration and tumorigenesis. Recently, alterations of KIBRA expression caused by promotor methylation have been reported for several types of cancer. Our current stud...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Schelleckes, Katrin, Schmitz, Boris, Lenders, Malte, Mewes, Mirja, Brand, Stefan-Martin, Brand, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844865/
https://ncbi.nlm.nih.gov/pubmed/29523820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22600-6
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