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ZFP226 is a novel artificial transcription factor for selective activation of tumor suppressor KIBRA

KIBRA has been suggested as a key regulator of the hippo pathway, regulating organ size, cell contact inhibition as well as tissue regeneration and tumorigenesis. Recently, alterations of KIBRA expression caused by promotor methylation have been reported for several types of cancer. Our current stud...

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Publicat a:Sci Rep
Autors principals: Schelleckes, Katrin, Schmitz, Boris, Lenders, Malte, Mewes, Mirja, Brand, Stefan-Martin, Brand, Eva
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844865/
https://ncbi.nlm.nih.gov/pubmed/29523820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22600-6
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