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ZFP226 is a novel artificial transcription factor for selective activation of tumor suppressor KIBRA

KIBRA has been suggested as a key regulator of the hippo pathway, regulating organ size, cell contact inhibition as well as tissue regeneration and tumorigenesis. Recently, alterations of KIBRA expression caused by promotor methylation have been reported for several types of cancer. Our current stud...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Schelleckes, Katrin, Schmitz, Boris, Lenders, Malte, Mewes, Mirja, Brand, Stefan-Martin, Brand, Eva
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844865/
https://ncbi.nlm.nih.gov/pubmed/29523820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22600-6
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