Загрузка...
Regulation of transcription functions of the p53 tumor suppressor by the mdm-2 oncogene.
BACKGROUND: Mdm-2, a zinc finger protein, negatively regulates the p53 tumor suppressor gene product by binding to it and preventing transcriptional activation (16). MATERIALS AND METHODS: Assays for p53 mediated transcription, repression and activation by mutant and wild-type p53 proteins were used...
Сохранить в:
| Главные авторы: | , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Feinstein Institute for Medical Research
1995
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2229942/ https://ncbi.nlm.nih.gov/pubmed/8529093 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|