RhoA/Rock activation represents a new mechanism for inactivating Wnt/β-catenin signaling in the aging-associated bone loss

The Wnt/β-catenin signaling pathway appears to be particularly important for bone homeostasis, whereas nuclear accumulation of β-catenin requires the activation of Rac1, a member of the Rho small GTPase family. The aim of the present study was to investigate the role of RhoA/Rho kinase (Rock)-mediat...

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Bibliografske podrobnosti
izdano v:Cell Regen
Main Authors: Shi, Wei, Xu, Chengyun, Gong, Ying, Wang, Jirong, Ren, Qianlei, Yan, Ziyi, Mei, Liu, Tang, Chao, Ji, Xing, Hu, Xinhua, Qv, Meiyu, Hussain, Musaddique, Zeng, Ling-Hui, Wu, Ximei
Format: Artigo
Jezik:Inglês
Izdano: Springer Nature Singapore 2021
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7925793/
https://ncbi.nlm.nih.gov/pubmed/33655459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13619-020-00071-3
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