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Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt–β-catenin and Wnt–RhoA–Rac1 pathways

Mutations in bone morphogenetic protein (BMP) receptor II (BMPRII) are associated with pulmonary artery endothelial cell (PAEC) apoptosis and the loss of small vessels seen in idiopathic pulmonary arterial hypertension. Given the low penetrance of BMPRII mutations, abnormalities in other converging...

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書誌詳細
主要な著者: de Jesus Perez, Vinicio A., Alastalo, Tero-Pekka, Wu, Jenny C., Axelrod, Jeffrey D., Cooke, John P., Amieva, Manuel, Rabinovitch, Marlene
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615088/
https://ncbi.nlm.nih.gov/pubmed/19139264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200806049
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