Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt–β-catenin and Wnt–RhoA–Rac1 pathways

Mutations in bone morphogenetic protein (BMP) receptor II (BMPRII) are associated with pulmonary artery endothelial cell (PAEC) apoptosis and the loss of small vessels seen in idiopathic pulmonary arterial hypertension. Given the low penetrance of BMPRII mutations, abnormalities in other converging...

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Detalhes bibliográficos
Main Authors: de Jesus Perez, Vinicio A., Alastalo, Tero-Pekka, Wu, Jenny C., Axelrod, Jeffrey D., Cooke, John P., Amieva, Manuel, Rabinovitch, Marlene
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615088/
https://ncbi.nlm.nih.gov/pubmed/19139264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200806049
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